Product involved: Mucosamin Spray

Treatment of symptomatic Oral Mucositis in Patients Undergoing Haematopoietic Stem Cell Transplantation (HSCT)

Study:

Treatment of symptomatic Oral Mucositis in Patients Undergoing Haematopoietic Stem Cell Transplantation (HSCT)

Design:

137 patients were divided in 4 groups:

  • Group A (37 patients): all received a complete session of professional oral health care (POHC) and Mucosamin spray on mucositis lesions 3-4 times a day after a meal.
  • Group B (32 patients): all received a complete session of professional oral health care (POHC) and Clorexidine 0.20%.
  • Group C (34 patients): received Mucosamin spray on mucositis lesions 3-4 times a day after a meal.
  • Group D (34 patients): received only Clorexidine 0.20% on oral mucositis lesions.

Measurements:

  • VAS scale.
  • Score for oral mucositis – WHO grade scale for oral mucositis: light mucositis WHO grade 1 and 2; severe mucositis WHO grade 3 and 4.

Oral mucositis prevalence

WHO grade of OM

OMAS grade of OM

Oral mucositis gravity

Clinical Results

• Treated patients with Mucosamin Spray developed less severe mucositis.
• Treated patients with Mucosamin Spray resolved the mucositis in less time.
• Maximum pain, measured with VAS scale, was lower in patients treated with Mucosamin Spray.

Other Clinical Evidence

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